中文名稱(chēng):7-溴靛紅

中文別名:7-溴吲哚-2,3-二酮;7-溴-1H-吲哚-2,3-二酮;7-溴吲哚-1H-2,3-二酮;7-溴-2,3-二氧代吲哚啉;7-溴吲哚滿二酮;

英文名稱(chēng):7-Bromoisatin

CAS號(hào):20780-74-9

性狀:深紅色粉末

含量:≥98%

分子式:C8H4BrNO2

分子量:226.0269

精確質(zhì)量:224.94300

密度:1.826g/cm3 

熔點(diǎn):199℃

折射率:1.649

PSA:46.17000
logP:1.72190

產(chǎn)品包裝:25kg紙板桶

儲(chǔ)存條件:干燥密封

檢測(cè)方法:核磁 液相

合成路線:

(2E)-n-(2-溴苯基)-2-(羥基亞氨基)乙酰胺(cas號(hào):101080-38-0)→7-溴靛紅(cas號(hào):20780-74-9)

(S,E)-tert-butyl 4-((7-bromo-2-oxoindolin-3-ylidene)methyl)-2,2-dimethyloxazolidine-3-carboxylate(cas號(hào):320734-34-7)→7-溴靛紅(cas號(hào):20780-74-9)+tert-butyl (R)-4-((R)-((S)-7-bromo-3-hydroxy-2-oxoindolin-3-yl)(hydroxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate(cas號(hào):320734-37-0)

2-溴苯胺(cas號(hào):615-36-1)→7-溴靛紅(cas號(hào):20780-74-9)

水合氯醛(cas號(hào):302-17-0)+2-溴苯胺(cas號(hào):615-36-1)→7-溴靛紅(cas號(hào):20780-74-9)

三氯乙醛(cas號(hào):75-87-6)+2-溴苯胺(cas號(hào):615-36-1)→7-溴靛紅(cas號(hào):20780-74-9)

tert-butyl (S,Z)-4-((7-bromo-2-oxoindolin-3-ylidene)methyl)-2,2-dimethyloxazolidine-3-carboxylate(cas號(hào):320734-36-9)→7-溴靛紅(cas號(hào):20780-74-9)

N-(2-bromophenyl)-2,2,2-trichloroacetamide(cas號(hào):349637-17-8)→7-溴靛紅(cas號(hào):20780-74-9)

oxalic acid bis(2-bromoanilide)(cas號(hào):60170-00-5)→7-溴靛紅(cas號(hào):20780-74-9)

上游原料:

(S,E)-tert-butyl 4-((7-bromo-2-oxoindolin-3-ylidene)methyl)-2,2-dimethyloxazolidine-3-carboxylate(cas號(hào):320734-34-7)

oxalic acid bis(2-bromoanilide)(cas號(hào):60170-00-5)

N-(2-bromophenyl)-2,2,2-trichloroacetamide(cas號(hào):349637-17-8)

tert-butyl (S,Z)-4-((7-bromo-2-oxoindolin-3-ylidene)methyl)-2,2-dimethyloxazolidine-3-carboxylate(cas號(hào):320734-36-9)

(2E)-n-(2-溴苯基)-2-(羥基亞氨基)乙酰胺(cas號(hào):101080-38-0)

三氯乙醛(cas號(hào):75-87-6)

2-溴苯胺(cas號(hào):615-36-1)

水合氯醛(cas號(hào):302-17-0)

下游產(chǎn)品:

tert-butyl (R)-4-((R)-((S)-7-bromo-3-hydroxy-2-oxoindolin-3-yl)(hydroxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate(cas號(hào):320734-37-0)